013 THE INFRAPATELLAR FAT PAD OF OSTEOARTHRITIC PATIENTS HAS AN INFLAMMATORY PHENOTYPE

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An emerging player in knee osteoarthritis: the infrapatellar fat pad

The role of inflammation in the development, progression, and clinical features of osteoarthritis has become an area of intense research in recent years. This led to the recognition of synovitis as an important source of inflammation in the joint and indicated that synovitis is intimately associated with pain and osteoarthritis progression. In this review, we discuss another emerging source of ...

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A Case of Infrapatellar Fat Pad Ganglion of the Knee

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Evaluation, Treatment, and Rehabilitation Implications of the Infrapatellar Fat Pad

CONTEXT The infrapatellar fat pad (IFP) is in the anterior knee compartment and may be a major pain generator. EVIDENCE ACQUISITION A PubMed database search using the terms Hoffas fat pad, anterior interval, and infrapatellar fat pad was performed from the years 1970 to 2015. STUDY DESIGN Clinical review. LEVEL OF EVIDENCE Level 5. RESULTS Limited research exists examining the role of t...

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Expression of calcitonin gene-related peptide in the infrapatellar fat pad in knee osteoarthritis patients

BACKGROUND The infrapatellar fat pad (IPFP) has been implicated as a possible source of osteoarthritis (OA) development and knee pain due to the production of inflammatory mediators and the existence of nerve fibers within this structure. Calcitonin gene-related peptide (CGRP) is a vasodilatory neuropeptide that is localized to joint tissues and has recently been implicated in the development o...

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Infrapatellar fat pad in the knee: is local fat good or bad for knee osteoarthritis?

INTRODUCTION Recent studies regarding the infrapatellar fat pad (IPFP) mainly focus on the roles of the cells derived from the IPFP. There have been few clinical or epidemiological studies reporting on the association between the IPFP and knee osteoarthritis (OA). Our objective is to generate hypotheses regarding the associations between IPFP maximum area and knee OA measures in older adults. ...

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ژورنال

عنوان ژورنال: Osteoarthritis and Cartilage

سال: 2010

ISSN: 1063-4584

DOI: 10.1016/s1063-4584(10)60040-4